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What is an interaction?
Mixing certain medicines together may cause a bad reaction. This is called an interaction. For example, one medicine may cause side effects that create problems with other medicines. Or one medicine may make another medicine stronger or weaker.
How do you classify the seriousness of an interaction?
The following classification is used:
Contraindicated: Never use this combination of drugs because of high risk for dangerous interaction
Serious: Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant: Potential for significant interaction (monitoring by your doctor is likely required)
Mild: Interaction is unlikely, minor, or nonsignificant